U petak, 4. aprila u 11 časova u Sali senata u zgradi Rektorata Univerziteta u Kragujevcu biće organizovano predavanje prof. Janisa Misirlisa sa Univerziteta u Patrasu, na temu " Bioreactors providing modular mechanical signals for tissue engineering".
Predavanje prof. Janisa Misirlisa sa Univerziteta u Patrasu
Apstrakt predavanja
“Bioreactors in tissue engineering: the importance of mechanical cues”
The use of bioreactors in tissue engineering applications is of paramount importance. The fate of the cells and their capacity to generate the appropriate tissue depends on many parameters, such as the overall scaffold properties, the biochemical milieu, and the mechanical environment.
It is well known that different tissues experience different mechanical stimuli, or combinations of such stimuli and examples will be given.
The design and construction of a modular bioreactor will be presented to demonstrate the response of cultured endothelial cells within a tube under a combination of flow, substrate stretching, and fast rotation. Attempts to relate the external mechanical cues to intracellular reorganization of the force carrying elements will be given.
“Bioreactors in tissue engineering: the importance of mechanical cues”
The use of bioreactors in tissue engineering applications is of paramount importance. The fate of the cells and their capacity to generate the appropriate tissue depends on many parameters, such as the overall scaffold properties, the biochemical milieu, and the mechanical environment.
It is well known that different tissues experience different mechanical stimuli, or combinations of such stimuli and examples will be given.
The design and construction of a modular bioreactor will be presented to demonstrate the response of cultured endothelial cells within a tube under a combination of flow, substrate stretching, and fast rotation. Attempts to relate the external mechanical cues to intracellular reorganization of the force carrying elements will be given.
